Publications on Nervous System Development and Neurodegeneration

Other Laboratory Publications


Semin Cell Dev Biol. (2018) pii: S1084-9521(18)30161-7. doi: 10.1016/j.semcdb.2018.10.007.

Impaired proteostasis in rare neurological diseases.

Osinalde N, Duarri A, Ramirez J, Barrio R, de Nanclares GP, Mayor U.

PMID: 30355526


Human Molecular Genetics (2018) 27(11):1955-1971. doi: 10.1093/hmg/ddy103.

Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.

Ramirez J, Lectez B, Osinalde N, Sivá M, Elu N, Aloria K, Procházková M, Perez C, Martínez-Hernández J, Barrio R, Grantz Šašková K, Arizmendi JM and Mayor U*

PMID: 29788202


Frontiers in Neuroscience (2018) 11:732. doi: 10.3389/fnins.2017.00732.

Drosophila melanogaster White Mutant w1118 undergo retinal degeneration

Ferreiro MJ*, Pérez C, Ruiz S, Marchesano M, Ruiz S, Caputi A, Aguilera P, Barrio R, Cantera R.

PMID: 29354028


Mol Neurodegener. 2017 Apr 11;12(1):29. doi: 10.1186/s13024-017-0170-3

Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.

Martinez A, Lectez B, Ramirez J, Popp O, Sutherland JD, Urbé S, Dittmar G, Clague MJ, Mayor U.

PMID: 28399880


PLoS One (2015) 10(10):e0139083. doi: 10.1371/journal.pone.0139083. eCollection 2015.

Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells.

Ramirez J, Martinez A, Lectez B, Lee SY, Franco M, Barrio R, Dittmar G, Mayor U*

PMID: 26460970


Journal of Innate Immunity (2015) 7(1):3-10s.

Do the genes of the innate immune response contribute to neuroprotection in Drosophila?

Cantera R*, Barrio R.

PMID: 25115549



PLoS One (2014) 9(5):e97703.

Global gene expression shift during the transition from early neural development to late neuronal differentiation in Drosophila melanogaster.

Cantera R*, Ferreiro MJ, Aransay AM, Barrio R.*

PMID: 24830291


Cell Mol Life Sci. 2014, 71(14):2747-58. doi: 10.1007/s00018-013-1526-7.

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10.

Lee SY, Ramirez J, Franco M, Lectez B, Gonzalez M, Barrio R, Mayor U.

PMID: 24292889


BMC Genomics. 2012 Sep 15;13(1):483.

Whole transcriptome analysis of a reversible neurodegenerative process in Drosophila reveals potential neuroprotective genes.

Ferreiro MJ, Rodríguez-Ezpeleta N, Pérez C, Hackenberg M, Aransay AM, Barrio R, Cantera R.

PMID: 22978642


Int J Dev Biol. 2011;55(6):603-11.

Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster.

Herboso L, Talamillo A, Pérez C, Barrio R.

PMID: 21948708


PLoS One. 2011;6(6):e21352. Epub 2011 Jun 21.

Efficient allele-specific targeting of LRRK2 R1441 mutations mediated by RNAi.

de Yñigo-Mojado L, Martín-Ruíz I, Sutherland JD.

PMID: 21712955


Dev Biol. 2004 Sep 1;273(1):121-33.

Regulation of R7 and R8 differentiation by the spalt genes.

Domingos PM, Brown S, Barrio R, Ratnakumar K, Frankfort BJ, Mardon G, Steller H, Mollereau B.

PMID: 15302602


Development. 2002 Aug;129(15):3575-84.

The role of TGF beta signaling in the formation of the dorsal nervous system is conserved between Drosophila and chordates.

Rusten TE, Cantera R, Kafatos FC, Barrio R.

PMID: 12117808


Development. 2002 Dec;129(24):5577-86.

Mutations in spalt cause a severe but reversible neurodegenerative phenotype in the embryonic central nervous system of Drosophila melanogaster.

Cantera R, Lüer K, Rusten TE, Barrio R, Kafatos FC, Technau GM.

PMID: 12421699


Development. 2001 Mar;128(5):711-22.

Spalt modifies EGFR-mediated induction of chordotonal precursors in the embryonic PNS of Drosophila promoting the development of oenocytes.

Rusten TE, Cantera R, Urban J, Technau G, Kafatos FC, Barrio R.

PMID: 11171396


Development. 1999 Jun;126(12):2653-62.

Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax.

de Celis JF, Barrio R, Kafatos FC.

PMID: 10331977



Other Laboratory Publications